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No jargon. No hype. What happens inside you, how it shows up in your day, and why we built MUTO the way we did. In five minutes.
Explained byDr Richie Barclay, Founder · PhD, cell biology and nutrition
Nothing dramatic happens overnight. But three quiet shifts start inside your 30 trillion cells, and they build through your 40s and 50s.
Every cell makes its own energy, in tiny power stations called mitochondria. NAD+ is the courier that carries energy from your food to them, over and over, all day. From your mid-30s, your body makes less of it. Fewer couriers, the same amount of work.
Your body responds less to the same food and the same training. It’s called anabolic resistance, and it’s what I spent years studying in the lab. Same effort, smaller return.
Making energy creates a little “exhaust”. The crews that clean it up, a family of enzymes called sirtuins, also run on NAD+. Fewer couriers means more competition for the same supply.
It’s not you doing anything wrong. It’s biology, and the basics you took at 30 weren’t built for it.
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It’s like your body has switched to low power mode. Still working, still getting through the day, but running on less than it used to.
The afternoon slump. Fewer couriers carrying energy from your food to your cells.
Less back from the same effort, and recovery that takes longer than it used to.
It’s not you. It’s biology, and the basics you took at 30 weren’t built for it.
MUTO is built for what you actually need after 35: one daily formula covering five jobs, so you’re not guessing across five separate pots.
19ingredients, every dose on the label
300mgNR, the most allowed in Great Britain
2capsules with breakfast
0proprietary blends
Your body turns NR into NAD+, CoQ10 and PQQ support your mitochondria, and active B vitamins help release energy from food.
NR 300mg, B12 (methylcobalamin) 100mcg, CoQ10 150mg, B2 (riboflavin) 5mg, Folate (5-MTHF) 400mcg, PQQ 20mg, B6 (P5P) 5mg, B1 (thiamine) 5mg, B3 (niacin) 16mg NE, B5 (pantothenic acid) 10mg, Biotin 300mcg, Copper bisglycinate 1mg
Vitamin D3 supports normal muscle function, CoQ10 and PQQ support the mitochondria that refill your energy, and riboflavin helps reduce tiredness.
CoQ10 150mg, D3 50mcg (2,000 IU), B2 (riboflavin) 5mg, PQQ 20mg
Active B vitamins, with zinc, support normal psychological function and mental performance through a demanding week.
B12 (methylcobalamin) 100mcg, Zinc bisglycinate 15mg, Folate (5-MTHF) 400mcg, B6 (P5P) 5mg, B1 (thiamine) 5mg, B3 (niacin) 16mg NE, B5 (pantothenic acid) 10mg, Biotin 300mcg
300mg NR paired with TMG, plus trans-resveratrol and grape seed polyphenols, vitamin K2 for your bones and zinc to help protect your cells.
NR 300mg, D3 50mcg (2,000 IU), TMG 450mg, B2 (riboflavin) 5mg, K2 (MK-7) 100mcg, Zinc bisglycinate 15mg, Trans-resveratrol 50mg, Grape seed extract 150mg
Vitamin D3, zinc, copper, folate and vitamins B6 and B12 all support the normal function of your immune system.
B12 (methylcobalamin) 100mcg, D3 50mcg (2,000 IU), Zinc bisglycinate 15mg, Folate (5-MTHF) 400mcg, B6 (P5P) 5mg, Copper bisglycinate 1mg
| Team | Who’s on it | What happens |
|---|---|---|
| The energy team | NR 300mg, CoQ10 150mg, PQQ 20mg, B2 (riboflavin) 5mg | NR becomes NAD+, the courier. CoQ10 is the relay runner that passes energy along inside the power station, and PQQ is studied for its role in the power stations themselves. B2 is part of the enzymes that release energy from food. |
| The B team | B1 (thiamine) 5mg, B3 (niacin) 16mg NE, B5 (pantothenic acid) 10mg, Biotin 300mcg | Each one is a working part in the steps that turn food into energy, and B1, B3 and B5 also support normal psychological function and mental performance. |
| The recycling team | Folate (5-MTHF) 400mcg, B12 (methylcobalamin) 100mcg, B6 (P5P) 5mg, TMG 450mg | Your cells constantly reuse one of their most important building blocks. Folate and B12 keep that recycling loop turning, TMG runs a second loop alongside it, and B6 handles the exit. We use the active forms, the ones the cell actually uses. |
| The clean-up crew | Zinc bisglycinate 15mg, Copper bisglycinate 1mg | Zinc and copper build the enzyme that cleans up the exhaust from making energy. One enzyme, two metals, so we pair them, both as bisglycinate. |
| The grape pair | Trans-resveratrol 50mg, Grape seed extract 150mg | Plant polyphenols from grapes. Trans-resveratrol is widely studied in healthy-ageing research, and grape seed extract is standardised to 95% polyphenols. |
| The bone relay | D3 50mcg (2,000 IU), K2 (MK-7) 100mcg | D3 tells your cells to make a bone protein. K2 switches that protein on. D3 makes it, K2 activates it. |
| The helper | BioPerine® (black pepper) 5mg | Black pepper extract, added to help your body take in the other ingredients. No taste, no heat. |
Plus BioPerine® (black pepper) 5mg in every serve, to help your body take in the rest. That’s all 19.
Vitamins B6 and B12 contribute to the reduction of tiredness and fatigue. Vitamin D contributes to normal muscle function. Vitamins D and K contribute to the maintenance of normal bones. Zinc, copper and vitamin D contribute to the normal function of the immune system. In a study of adults aged 40 to 60, 300mg of NR a day raised NAD+ by 51% in two weeks. That study tested NR on its own, not MUTO.
Most people in their 40s and 50s are taking some mix of these. Here’s how they compare.
| MUTO | Multivitamin | Greens powder | Collagen or joint capsules | |
|---|---|---|---|---|
| Built for | What you need after 35: five jobs | The basics | The basics | One area |
| NR, for NAD+ | ✓ 300mg | Not usually included | Not usually included | Not usually included |
| Active (methylated) B vitamins | ✓ | Varies: check the label | Varies: check the label | Not usually included |
| Vitamin D3 with K2 | ✓ 2,000 IU + 100µg | Varies: check the label | Varies: check the label | Not usually included |
| Zinc and copper, dosed as a pair | ✓ 15mg + 1mg | Varies: check the label | Varies: check the label | Not usually included |
| Every dose on the label | ✓ All 19 | Varies: blends are allowed | Varies: blends are allowed | Varies |
| Every batch third-party tested | ✓ | Not required by law | Not required by law | Not required by law |
| Scientists with names | ✓ PhD founder + six-member board | Varies | Varies | Varies |
| 90-day money-back guarantee | ✓ | Varies | Varies | Varies |
| How many pots | One jar | One of several | One of several | One of several |
Comparisons are by category, not brand, and products vary. Hold any label up against ours. Multivitamins, greens and collagen do the job they were built for; MUTO was built for a different one.
A supplement doesn’t need a scientist anywhere near it. Ours has seven. Our scientific advisory board meets every quarter to guide our research and every new formula.
PERFORMANCE NUTRITIONIST, INTERNATIONAL RUGBY
LONGEVITY DOCTOR & GLOBAL SPEAKER
LEADING METABOLISM RESEARCHER
PERFORMANCE & SLEEP DOCTOR
Longevity & Human Optimisation Doctor & Founder of Levitas One
Longevity doctor and medical educator
Our research. Our first human study starts in December 2026 at the University of Westminster, with work at King’s College London, Coventry and Newcastle to follow. There are no results yet, and we’ll never say there are. We’ll publish them, whatever they show.
Our advisory board guides our research and formulation. Its members don’t endorse products, and none of them is presented as recommending MUTO for any medical purpose.
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What people tell us they notice, and roughly when. Everyone’s different, so score yourself on day 1 and compare.
Score your afternoons, sleep and recovery out of 10, or note your wearable’s numbers. Then two capsules with breakfast.
Usually the first thing people notice. B vitamins help reduce tiredness and fatigue, and NR tops up the NAD+ your cells use to make energy. Less of a 3pm slump, and energy left for the evening.
Vitamin D supports normal muscle function, and CoQ10 and PQQ support your mitochondria. A walk, a round of golf or a gym session stops hanging around for days.
Compare your scores with day 1. Many people say they hadn’t realised how flat they’d been feeling. Not for you? Get every subscription payment back.
Based on what customers tell us, not a clinical study. Everyone’s different.
£2 a day on the monthly plan
First order includes:
A 250g pouch of micronised creatine
A glass jar to keep
How to run your 90 days and check it yourself
Size UK 6–11
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